Longvida Curcumin - dokumentert å ha 65 ganger høyere biotilgjengelighet

Curcumin, det gule fargestoffet fra gurkemeie er et av de mest spennende virkestoffer naturen tilbyr oss, med snart 6000 publiserte studier som viser potensielle og spennende helsegevinster.  Ulempen med curcumin er at kroppen vår har vanskeligheter med å ta opp curcumin.  Biotilgjengeligheten er altså lav, noe som krever høye doser for å oppnå disse helsegevinstene.

Longvida Curcumin er en ny form for curcumin hvor man har greid å øke biotilgjengeligheten med hele 65 ganger, sammenlignet med vanlig curcumin-ekstrakter.  Longvida Curcumin finner du i Reumex Curcumin fra Biosan, et produkt spesiallaget for å lindre ømme og stive ledd.

Under følger en kort teskt om hva som gjør Longvida Curcumin så unik, og hvorfor kun små doser gir stor gevinst:

LCP™ (Solid Lipid Curcumin Particle Technology) is the ideal absorption-promoting system, based on real, live research data using validated analytical methodologies.

The SLCP™ technology fulfills the three main requirements for bioavailability: 1) solubility 2) permeability 3) stability

Solubility: SLCP™ dissolves curcumin into a lipid particle.　 When this particle enters the bile acids in the small intestine, it dissolves into the bile acids where it is able to be taken up into the bloodstream.

Permeability: with SLCP™, the curcumin is in a form that is permeable through the lining of the small intestine.　 Permeability has to do with ionization of the compound.　 Regular curcumin　is in a non-ionized form, while SLCP is considered to provide a more　ionized form.

Stability: SLCP™ protects curcumin from degradation by different pH (acidic in stomach and basic in small intestine).　 In many curcumin pK studies, all they find are ferulic acid and vanillin, which are degradation products of curcumin, or curcumin glucuronide, which is an inactive conjugate of curcumin

The SLCP™ technology should not be confused with the liposomal technology.　 Before UCLA developed Longvida®, they considered liposomes as a possible technology to improve curcumin delivery, however it was determined that liposomes were not ideal for oral dosing due to their poor shelf stability and instability in the gut after oral dosing.　

Longvida® is stable on the shelf and after oral consumption in the gut, allowing for therapeutic levels of the free form of curcumin in the blood stream as a possible technology to improve curcumin delivery.

Kjøp Curcumin / Longvida® her

Kilde:

Safety and pharmacokinetics of a solid lipid curcumin particle formulation in osteosarcoma patients and healthy volunteers.  Gota et al., J Agric Food Chem., 2010 Feb 24;58(4):2095-9. 

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